Symbol
Name
ID

Lrp6
low density lipoprotein receptor-related protein 6
MGI:1298218

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Photophobia
Disease(s) Associated with LRP6	Photophobia
tooth agenesis

Mouse Phenotypes

abnormal neural tube closure

spina bifida

spina bifida cystica

spina bifida occulta

craniorachischisis

abnormal orientation of outer hair cell stereociliary bundles

abnormal forebrain development

abnormal midbrain-hindbrain boundary morphology

forebrain hypoplasia

abnormal midbrain morphology

absent inferior colliculus

abnormal forebrain morphology

abnormal telencephalon morphology

abnormal cerebellum morphology

exencephaly

fused dorsal root ganglion

Availability

Mouse Genotype

Lrp6^Cd/Lrp6^Cd

Lrp6^Gt(Ex187)Byg/Lrp6^Gt(Ex187)Byg

Lrp6^Gw/Lrp6^Gw

Lrp6^m10Bei/Lrp6^m10Bei

Lrp6^rs/Lrp6^rs

Lrp6^skax26/Lrp6^skax26

Lrp6^tm1.2Cjz/Lrp6^tm1.2Cjz

Lrp6^Cd/Lrp6^Gt(Ex187)Byg

Lrp6^Gw/Lrp6⁺

Lrp6^tm1.2Cjz/Lrp6^Gt(Ex187)Byg

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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